2Uz.Dr., Devrek Devlet Hastanesi, Göz Hastalıkları Kliniği, Zonguldak - TÜRKİYE
3Asist.Dr., Marmara Üni. Tıp Fak., Göz Hast. Anabilim Dalı, İstanbul - TÜRKİYE
4Uz.Dr., Marmara Üni. Tıp Fak., Göz Hast. Anabilim Dalı, İstanbul - TÜRKİYE
5Prof.Dr., Marmara Üni. Tıp Fak., Göz Hast. Anabilim Dalı, İstanbul - TÜRKİYE Purpose: We aimed to evaluate choroidal thickness in uveitic glaucoma (UG) patients using enhanced depth imaging optical coherence tomography (EDI-OCT) and to compare with healthy control subjects.
Materials and Methods: This study was planned as a cross-sectional, non-randomized case series. The patients in UG group didn?t have any ocular disease except for uveitis and glaucoma, while control group included healthy subjects. The subjects who had an ocular surgery or uveitis attack within the last 3 months or had any other systemic disease were excluded from the study. All participants underwent a complete ophthalmologic examination. Choroidal thickness was measured between outer layer of retinal pigment epithelium and inner layer of sclera, at subfoveal region and 500 ?m temporal and 500 ?m nasal to the fovea.
Results: Fourteen eyes of 14 uveitic glaucoma patients (7 female, 7 male, mean age: 44.7±14.2) and 20 eyes of 20 healthy subjects (10 female, 10 male, mean age: 44.9±16.2) were included to the study. Groups were homogeneous in terms of age, laterality, IOP, axial length and central corneal thickness. (P > 0.05) Mean subfoveal choroidal thickness was 334.5±91?m in UG group and 339.7±42.3?m in control group. (P =0.82) Mean choroidal thickness in subfoveal, temporal and nasal regions was 325.2±94.4, 334.5±91.0, 328.6±94. 4?m in UG group and 317.1±67.8, 329.5±68.3, 309.9±73.2 ?m in control group, respectively. There was no statistically significant difference in any of the measured regions between the groups.
Conclusion: We did not observe any choroidal thinning in subfoveal or perifoveal regions in UG compared to healthy subjects. These results suggest that mechanical hypothesis might be more prominent in the pathogenesis of UG rather than ischemic hypothesis.
Keywords : Choroidal thickness; EDI OCT; Uveitic glaucoma; Uveitis