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¹Dicle Üniversitesi Tıp Fakültesi, Göz Hastalıkları A.D., Diyarbakır, Yard. Doç. Dr.
²Dicle Üniversitesi Tıp Fakültesi, Psikiyatri A.D., Diyarbakır, Yard. Doç.Dr.
³Dicle Üniversitesi Tıp Fakültesi, Göz Hastalıkları A.D., Diyarbakır, Prof. Dr. Purpose: Ta investigate, the relationship between depression and glaucoma and topical antiglaucoma treatment.
Materials and Methods: A total of 120 patients with glaucoma who were treated with topical antiglaucoma agents were included in the study. Mean age of the patients was 52.37±16.46 years: 64 patients were male and 56 were female. The patients receiving antiglaucomatous treatment were evaluated in two separate groups: those who used topical beta blockers and those who used topical prostaglandin analogues. In addition, 60 subjects of the same age group, who had no systemic or ophthalmologic diseases except for refractive errors, were included in the study as controls. Mean age of those subjects in the control group was 51.80±13.96: 36 of controls were male and 24 female. All subjects included in the study were evaluated through, sociodemographic data form, Structural Clinical Interview for DSM-IV (SCID) for diagnosis of depression, and Beck Depression Inventory (BDI) for the severity of depression.
Results: The depression rate in the glaucoma group (25.2%) was higher than that in the control group (10%) (p=0.013). The depression rate was 29.5% in patients who used beta blockers and 22.03% in those using prostaglandin analogues, and statistically there was no significant difference between them (p=0.350). However, the severity of depression according to BDI score was higher in patients who used beta blockers than those in the other group who used prostaglandin analogues (p=0.010), as well as the controls (p=0.000).
Conclusion: The depression rate was higher in patients with glaucoma with respect to the controls. Also, the average depression score was found to be higher in patients who used topical beta blockers as treatment in than those who used prostaglandin analogues. We are of the opinion that this situation should be taken into consideration in patients with glaucoma and in those using beta blockers. Keywords : Beta blocker, depression, glaucoma, prostaglandin analogue