Turkish Abstract Abstract PDF Similar Articles Mail to Author

¹S.B. Ulucanlar Göz Eğitim ve Araştırma Hastanesi, Ankara, Uzm. Dr.
²S.B. Ulucanlar Göz Eğitim ve Araştırma Hastanesi, Ankara, Asist. Dr.
³Gazi Üniversitesi Tıp Fakültesi, Halk Sağlığı A.D., Ankara, Doç. Dr.
⁴S.B. Ulucanlar Göz Eğitim ve Araştırma Hastanesi, Ankara, Doç. Dr. Purpose: To evaluate the central corneal thickness (CCT) values in Primary Open Angle Glaucoma (POAG), Pseudoexfoliation Glaucoma (PXG), Normal Tension Glaucoma (NTG), Ocular Hypertension (OHT), and normal subjects, and to study the relationship of age, gender, intraocular pressure (IOP) and systemic diseases with CCT.
Materials and Methods: A total of 286 patients and 50 control subjects were included in our prospective study. All the patients were questioned for family history of glaucoma and presence of systemic diseases. IOP and CCT were measured using Goldmann applanation tonometer and ultrasound pachymeter, respectively
Results: Only CCT values of NTG (527.8±21.4 μm) and OHT (578.6±24.1 μm) were statistically significantly different from the values of the control group (545.9±39.3 μm). Age and IOP were found to be statistically important factors those affecting CCT in multivariate analysis. Systemic diseases were found to have no significant effect on CCT values. The NTG group had significantly higher rates of diabetes mellitus, hypertension, and hyperlipidemia, while we found no relationship between migraine and NTG in our cases. The rate of positive family history of glaucoma was found to be significantly higher in OHT patients than other cases and normal subjects.
Conclusions: NTG and OHT patients have significantly lower and higher CCT values, respectively. There was a moderate thinning of cornea by ageing. DM and HT did not seem to have a relation with CCT. Keywords : Central corneal thickness, intraocular pressure, ocular hypertension, glaucoma, systemic disease