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¹M.D. Associate Professor, Ulucanlar Training and Research Hospital, Eye Clinic, Ankara/TURKEY
²M.D. Professor, Ulucanlar Training and Research Hospital, Eye Clinic, Ankara/TURKEY Purpose: A patient was admitted to the emergency department with a sudden loss of vision and pain in the right eye. Visual acuity was P+P+ and intraocular pressure (IOP) was 6 mmHg at the initial examination. There was a mild corneal edema and keratic striate in the cornea. The anterior chamber was shallow and dense pigmented membrane was observed on the pupillary area. Needling and subconjunctival injection of 5-Fluorouracil (5-FU) was performed on the patient 3 days before. The patient was found to have a toxic reaction related with 5-FU, and hospitalized for the treatment. In this article, a case with hypotonia and severe toxic reaction and complications related with needling and subconjunctival injection of 5-FU were discussed. Keywords : Needling, 5-fluorouracil, trabeculectomy, bleb failure