TJ-CEO
2018 , Vol 13 , Num 2
Indapamide-Induced Transient Myopia, Choroidal Thickening and Angle Closure: A Case Report
1Yrd. Doç. Dr., Ordu Üniversitesi Tıp Fakültesi, Göz Hastalıkları Ana Bilim Dalı, Ordu, Türkiye2Yrd. Doç. Dr., Giresun Üniversitesi Tıp Fakültesi, Göz Hastalıkları Ana Bilim Dalı, Giresun, Türkiye Sulphonamide-derived drugs may cause morphological changes in the ciliary body and uveal tract. Ciliary body swelling and cilio-choroidal effusion associated with indapamide (a sulfa-derivative diuretic, antihypertensive agent) intake have been demonstrated through ultrasound biomicroscopy (UBM) and classic ultrasonography previously. A 52-year-old male patient suffering from acute blurred vision and a dull eye pain referred to the ophthalmology clinic. The indapamide (1.5 mg tablet once a day) was prescribed to the patient two weeks before for essential hypertension. Bilateral signifi cant myopic shift and intraocular pressure (IOP) elevation were determined at the initial examination. Anterior segment and enhanced depth imaging optical coherence tomography (EDI-OCT) scans revealed shallow anterior chamber, angle closure and choroidal thickening. This case is the third presentation with bilateral angle closure and increase in intraocular pressure (IOP) due to indapamide use and fi rst one demonstrating choroidal thickening via EDI-OCT as a novel follow-up instrument. Keywords : indapamide, optical coherence tomography, choroid, myopia, anterior chamber