Material and Methods: The 167 eye of 87 subjects were examined after pupillary dilation with optical coherence tomography (Stratus OCT, model 3000).There were 3 groups; OHT group 1 (n=36), OAG group 2 (n=85), control group, group 3 (n=46). The results of RNLF thickness (mean, superior, inferior, nasal, temporal) were recorded and compared statistically.

Results: Central corneal thickness (CCT) was 577.7±24.8 μ in group 1 whereas 557.0±34.6 μ in group 2 and 541.8±32.3 μ in group 3. The measurement of CCT was significantly thicker in group 1 than that of group 2 and 3 (p<0.05). RNLF thicknesses (mean, superior, inferior, nasal, temporal) were 103,1±9,3, 124.3±15,8, 134.6±14.5, 85.4±19.6, 67.9±11.8 μ respectively in group 1, whereas 84.9±17.0, 101.5±25.6, 107.8±26.0, 67.8±18.9, 61.1±16,6 μ in group 2 and 98.3±11.3, 117.3±25.6, 127.9±24.1, 77.2±16, 66.2±11.4 μ in group 3. Although there was no statistically significant difference between group 1 and group 3 regarding the mean and all quadrant thicknesses, there was a significant difference amoung groups at all quadrants except temporal quadrant (p<0.001).

Conclusion: RNLF thickness analysis with Stratus OCT is an effective and reliable method in detection and evaluation of glaucoma patients. It can provide a significant contribution to other diagnostic methods. Keywords : Glaucoma, ocular hypertension, santral corneal thickness, optic coherence tomography, retina nerve fiber thickness