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¹M.D. Associate Professor, Ulucanlar Eye Training and Research Hospital, 1st Eye Clinic, Ankara/TURKEY
²M.D., Ulucanlar Eye Training and Research Hospital, 1st Eye Clinic, Ankara/TURKEY Purpose: To compare the corneal biomechanical parameters of cases with Behçet's disease (BD) and normal subjects by ocular response analyzer (ORA).
Material and Methods: Fifty two eyes of 52 cases with BD and 26 eyes of 26 normal subjects were enrolled to our prospective study. Cases with BD were divided into two groups according to the number of uveitis attacks within the last 1 year. Group 1 consisted of 25 eyes of 25 cases who had at least 1 attack under systemic treatment, group 2 consisted of 27 eyes of 27 cases who had no uveitis attack with or without systemic treatment for the last 1 year. Group 3 consisted of 26 eyes of 26 control subjects. None of the cases in the study had glaucoma and taken any anti-glaucoma treatment before. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated intraocular pressure (IOPg) of the cases were measured by ORA. The comparison of the results was performed by Anova, Shapiro-Wilk, post-hoc tukey and chi-square tests for the statistical analysis.
Results: There were no statistically significant differences in GAT (p=0.1), IOPg (p=0.07), CRF (p=0.11) and IOPcc (p=0.75) between the groups. But the mean CH was found to be significantly higher in control subjects than group 1 and 2 (p=0.04).
Conclusion: Because of the low values of CH of the cases with BD, the changes in corneal biomechanics was thought to be related with relapsing uveitis and/or corticosteroid use. Keywords : Behçet’s disease, cornea, corneal biomechanics, ocular response analyzer