Materials and Methods: This retrospective study included 94 eyes with PXS, 77 eyes with PXG and 109 normal eyes. Anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), central corneal thickness and keratometry values, measured by Scheimpflug imaging before and after surgery at first month and 3rd months, were compared among the three groups. The influence of intraocular pressure (IOP) change on AS was analyzed by correlation analysis.

Results: The ACA and change in ACA were significantly smaller in normals among the three groups (p<0.0001) at month 1 and 3. The ACV (p=0.04) and enlargement in ACV (p=0.01) were significantly greater in the PXS eyes than PXG eyes, at month 3. The only significant correlation between AS and IOP was in the PXG group (p<0.05). At month 1, the IOP reduction was correlated with change in ACD (R=-0.230) and in ACV (R=-0.278), and also IOP was correlated with change in ACA (R=-0.230). At month 3, the postoperative IOP was associated with postoperative ACV (R=-0.240).

Conclusion: In the PXG group, greater reduction in IOP was correlated with deepening in ACD and ACV and also higher postoperative IOP was correlated with less enlargement in ACA and smaller ACV. The eyes with pseudoexfoliation may be more sensitive to IOP changes following cataract surgery in the presence of glaucoma due to greater zonular instability. Keywords : Anterior segment, Cataract surgery, Intraocular pressure, Zonular instability